Ongoing Observational Trials

SEAR

Acute stress can affect how we think, make decisions, and adapt to changing situational demands. One important skill - cognitive flexibility - helps us shift between different ways of thinking and problem-solving. This ability is essential for everyday life, yet we still have much to learn about how acute stress impacts it.

In this study, we will explore how a short, real-world stress experience influences different aspects of cognitive flexibility. Participants will complete a series of computer- and conversation-based activities before and after a brief stress task. Throughout the session, we will collect biological, physiological, and self-report measures to understand how the body and mind respond to these experiences.

We will also collect samples such as saliva, hair, and blood to measure biomarkers and hormone levels. Participants will return one week later for a short follow-up session to see if any effects last over time.

Currently Recruiting!
Eligible gender: All gender identities welcome
Eligible ages: 18 to 60

You are eligible if you:

  1. Are between the ages of 18 and 60

  2. Can read and write in English

  3. Are willing to attend three in-person sessions and one short at-home session

  4. Agree to provide biological samples (urine, hair, saliva, blood) and follow pre-session restrictions (no caffeine, nicotine, exercise, or food for 2 hours before; no recreational drugs for 24 hours before)

  5. Have no diagnosed or suspected mental health disorder

You are not eligible if you:

  1. Have any diagnosed or suspected psychiatric disorder (e.g., depression, anxiety, OCD, ADHD, autism, psychotic disorders, etc.)

  2. Have endocrine, metabolic, autoimmune, cardiovascular, or chronic pain disorders

  3. Are currently pregnant

  4. Regularly take psychiatric or anti-inflammatory medications

  5. Have a strong fear of needles or history of fainting during blood draws

  6. Have any medical or safety concerns as determined by the study investigators

Those who are eligible and complete the entire study will receive $60 as compensation for participating.

Recruitment form for SEAR study

Note: Only those participants deemed eligible will be contacted with further information and steps

RAVES

Considering the lack of effective treatments given to Canadian military veterans for the treatment of PTSD, mood disorders, and pain, RAVES (rolling-basis observational trial on psychedelic-assisted psychotherapy) is a soon-to-be-launched observational trial in which we have partnered with Heroic Hearts Canada to explore the efficacy of psychedelic-assisted psychotherapy in Canadian Veterans.

Check back soon for enrollment opportunities!

Note: Only those participants deemed eligible will be contacted with further information and steps